The beloved medical sitcom "Scrubs" is set to make its highly anticipated return with a 10th season, premiering on ABC on February 25 with a special double episode. After a sixteen-year hiatus, fans can look forward to another dose of medical mirth as the original gang reunites at Sacred Heart Hospital. The release of the first full-length trailer has confirmed the return of fan-favorite characters and the introduction of new faces, promising a blend of nostalgic humor and fresh storylines.

Key members of the original cast are reprising their iconic roles. Zach Braff returns as Dr. John "J.D." Dorian, Donald Faison as his best friend Dr. Christopher Turk, Sarah Chalke as Dr. Eliot Reid, Judy Reyes as Nurse Carla Espinosa, and John C. McGinley as the notoriously curmudgeonly Dr. Perry Cox. The trailer reveals that while a decade and a half has passed, much remains the same: J.D. and Turk are still inseparable, their signature "Eagle!" move perhaps less agile with age; Eliot continues to struggle with rhythm, much to Carla's amusement; and Dr. Cox remains his characteristic jerk, humorously noting he's on his 900th strike when asked to tone it down by newcomer Sibby.

The new season will see the returning doctors tasked with the challenging job of training a "motley crew" of new medical interns, described as having shaky hands and aversions to blood. This generational clash and mentorship theme is expected to drive much of the season's narrative. Alongside the original stars, the revival introduces new cast members including Vanessa Bayer (as Sibby), Joel Kim Booster, Ava Bunn, Jacob Dudman, David Gridley, Layla Mohammadi, and Amanda Morrow. Robert Maschio and Phill Lewis from the original series' cast will also make a return, adding to the ensemble.

"Scrubs" was originally created by Bill Lawrence, whose inspiration for the show came from the experiences of his friend, Dr. Jonathan Doris, after whom the main character J.D. was named. The series first premiered on NBC in 2001, captivating audiences with its unique blend of comedy, drama, and J.D.'s internal monologues, following his early years as a doctor navigating complex doctor-patient relationships, eccentric co-workers, and the absurd realities of the medical profession. After seven seasons on NBC, the show was cancelled in 2008 but was subsequently picked up by ABC for an eighth season in 2009.

The show had a somewhat complex ending history. The two-part season 8 finale, "My Finale," was initially conceived as the series conclusion, depicting J.D.'s departure from Sacred Heart to be closer to his son. It showed him seeking a perfect last day, finding closure with his nemesis the Janitor (Neil Flynn), and envisioning a future with Eliot and his friends. However, ABC renewed the show for a ninth season in 2010. This ninth season, initially pitched as a spinoff titled "Scrubs: Medical School," shifted its focus to a new group of interns, with only Donald Faison and John C. McGinley returning as series regulars, and Zach Braff appearing in a reduced capacity. This incarnation ran for a single 13-episode season before the series concluded again.

For the upcoming revival, "Scrubs" veterans Tim Hobert and Aseem Batra will serve as executive producers and showrunners. Additional executive producers include Zach Braff, Donald Faison, Sarah Chalke, and Bill Lawrence (via Doozer Productions), alongside Randall Winston, Jeff Ingold, and Liza Katzer. The series is produced by 20th Television and will debut on ABC on February 25 at 8 p.m. ET/PT. All episodes of the revival will also be available to stream on Hulu, making it accessible to a wide audience. Fans are encouraged to stay tuned for future updates from Collider.