Chloe Rose, a 25-year-old beautician from Stanwell, Surrey, embarked on a challenging journey to conceive a child with her husband, Jack, starting in 2019. After years of unsuccessful attempts and negative pregnancy tests, the couple was accepted into an NHS fertility treatment trial in January 2024. However, their hopes were soon dashed when Chloe was removed from the trial due to her weight. This setback underscored for Mrs. Rose the critical need to lose weight if she wished to pursue any further fertility treatments.

Despite her determination, Chloe had previously struggled with weight loss, trying various diets and exercise routines, including regular gym attendance while on the trial, all to no avail. Her difficulties were compounded by underlying health conditions such as polycystic ovary syndrome (PCOS), arthritis, and the use of steroid medication, which made shedding weight particularly challenging.

In July 2024, driven by her dream of starting a family, Mrs. Rose decided to order Mounjaro from an online pharmacy, costing £135. This proved to be a turning point; within just five months, she achieved a significant weight loss of six stone, transforming from a size 20 to a size 10. While Chloe chose not to disclose her exact starting weight, the rapid change was remarkable, especially given her long-standing struggles.

Weeks after discontinuing the Mounjaro jab, Chloe and Jack received the astonishing news on January 20, 2025 – she was pregnant. This came as a profound surprise, particularly because Chloe had not experienced a menstrual period for six years due to the severity of her PCOS. The unexpected pregnancy, conceived without a prior period, filled her with immense joy and excitement, signaling the culmination of six years of trying to conceive. On September 18, 2025, their baby girl, Jeanie, was born, weighing 5lbs 1oz.

Chloe Rose attributes her ability to conceive to the weight loss she achieved, with Mounjaro playing a crucial role in initiating that process. She stated, "Mounjaro helped to give me the baby I'd always hoped for. I think that the weight loss is massively what did it, but Mounjaro definitely kickstarted that journey for me." However, she offers a cautious perspective, emphasizing that Mounjaro may not be suitable for everyone and its effectiveness in facilitating pregnancy depends on the individual's underlying reasons for fertility struggles. She clarified that while it helped her, it won't universally lead to pregnancy.

Chloe's experience highlights a broader trend: a University College London study indicated that approximately 1.6 million adults in England, Wales, and Scotland used weight loss drugs like Wegovy and Mounjaro between early 2024 and early 2025. This period has also seen a documented increase in "Mounjaro babies," with some users conceiving even while on contraception. Medical professionals suggest that the weight loss induced by these drugs can enhance fertility by reducing inflammation and regulating the menstrual cycle. Additionally, potential side effects such as vomiting could interfere with the absorption of contraceptive pills, thereby increasing the likelihood of an unexpected pregnancy.

In response to such developments, Lilly, the manufacturer of Mounjaro (tirzepatide), issued a statement. They stressed that Mounjaro should only be used when prescribed by a licensed healthcare professional and supplied by registered pharmacies or providers. The company encourages patients to consult their doctors to discuss any potential side effects and to ensure they are receiving genuine Lilly medicine, underscoring the importance of medical supervision and authentic medication.