A major wildfire in eastern Crete has forced the evacuation of thousands of people and caused widespread damage to homes and businesses, as strong winds continue to hamper firefighting efforts.

The blaze, which broke out on Wednesday afternoon near the village of Achlia, has spread rapidly across forested and mountainous terrain due to gale-force winds and high temperatures.

According to Greece's fire service, the fire has now split into three active fronts - in Achlia, Ferma and Skinokapsala.

Crews say the conditions are creating new flare-ups, making containment efforts extremely difficult.

Authorities have ordered the mass evacuation of hotels, rental rooms and homes in the Ferma municipality. The operation is underway with the support of the fire service, police and local volunteers.

Around 5,000 people have been evacuated, the majority of whom are foreign tourists staying in local hotels, Manolis Tzarakis, president of the Ierapetra and Southeast Crete Hoteliers' Association, told a local radio station on Thursday.

At least 200 evacuees are being sheltered in a sports hall in Ierapetra.

As of Thursday morning, a total of 230 firefighters, supported by 13 specialised foot teams, 46 engines, and a drone surveillance unit, had been deployed. Ten helicopters have been made available.

Authorities say the damage is extensive, with homes, greenhouses, villas, hotels and businesses reportedly destroyed in both coastal and inland areas.

In the settlement of Agia Fotia, homes and rental properties have been destroyed, and the area is experiencing a power outage, according to local reports.

The main road near Agia Fotia has been closed by police, who have urged residents and visitors to avoid all non-essential travel due to hazardous air quality, extreme heat and falling ash.

As a precaution, all hospitals in Crete have been placed on alert by health authorities.

Emergency alerts via the 112 public warning system were issued throughout Wednesday, calling for evacuations from Achlia, Ferma, Agia Fotia, Galini, and later Koutsounari, instructing residents and tourists to move towards Ierapetra.

Some individuals who were cut off by road were reportedly evacuated by boat from local beaches.

Meanwhile in Turkey, an elderly man and a forestry worker have died in western Turkey as a result of wildfires in the west of the country.

At least six heat-related deaths have been reported in Europe as the continent reels under an early summer heatwave. The latest recorded fatalities were in Spain and Italy. There were also casualties in France.

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