AFP photographs showed the wounded being treated in a tented area at Gaza City’s Al-Ahli Hospital, also known as the Baptist Hospital, with parish priest Father Gabriel Romanelli with a bandage around his lower leg.

Some of the wounded arrived on stretchers, with one man wearing an oxygen mask.

The patriarchate, which has jurisdiction for Catholics in Israel, the Palestinian Territories, Jordan and Cyprus, condemned the strike and said it “destroyed large parts of the complex”.

“Targeting a holy site currently sheltering approximately 600 displaced persons, the majority of whom are children and 54 with special needs, is a flagrant violation of human dignity and a blatant violation of the sanctity of life and the sanctity of religious sitses, which are supposed to provide a safe haven in times of war,” it said.

Israel expressed “deep sorrow” over the damage and civilian casualties, adding that the military was investigating.

“Israel never targets churches or religious sites and regrets any harm to a religious site or to uninvolved civilians,” the foreign ministry said on X.

Italian Prime Minister Giorgia Meloni said attacks on civilians in Gaza were “unacceptable” while her Foreign Minister Antonio Tajani called the church attack “a serious act against a Christian place of worship”.

Out of the Gaza Strip’s population of more than two million, about 1,000 are Christians. Most of them are Orthodox but according to the Latin Patriarchate, there are about 135 Catholics in the territory.

Since the early days of the war which erupted in October 2023, members of the Catholic community have been sheltering at the Holy Family Compound in Gaza City, where some Orthodox Christians have also found refuge.

Pope Francis repeatedly called for an end to the war and in his final Easter message, a day before his death on April 21, he condemned the “deplorable humanitarian situation” in the Palestinian territory.

Monsignor Pascal Gollnisch, the head of Catholic charity l’Oeuvre d’Orient, told AFP the raid was “totally unacceptable”.

“It is a place of worship. It is a Catholic church known for its peaceful attitude, for being a peacemaker. These are people who are at the service of the population,” he said.

“There was no strategic objective, there were no jihadists in this church. There were families, there were civilians. This is totally unacceptable and we condemn in the strongest possible terms this attitude on the part of Israel.”

More than 21 months of war have created dire humanitarian conditions for Gaza’s population, displacing most residents at least once and triggering severe shortages of food and other essentials.

The war was triggered by a Hamas attack on Israel, which resulted in the deaths of 1,219 people, most of them civilians, according to an AFP tally based on official figures.

Israel’s retaliatory military offensive has killed at least 58,573 Palestinians, mostly civilians, according to the health ministry in Hamas-run Gaza.

Media restrictions in Gaza and difficulties in accessing many areas mean AFP is unable to independently verify the tolls and details provided by the civil defence agency and other parties.