Eric Dane Speaks: The Diane Sawyer Interview launches Thursday, June 19 on Hulu and Disney+, marking the actor’s first public comments since his ALS diagnosis.

Shot as an extended cut of his Good Morning America appearance, the IMPACT x Nightline special sees Dane in conversation with Sawyer for a revealing, hour-long sit-down. The former Grey’s Anatomy and Euphoria star speaks openly about his symptoms, the timeline of his diagnosis, and how he’s approaching what comes next.

More than a profile, the episode also engages with the broader context of ALS in 2025. Dr. Merit Cudkowicz, Chief of Neurology at Massachusetts General Hospital and a globally recognized ALS researcher, joins the conversation to unpack current science, shifting patient trends, and why diagnoses have climbed in recent years.

There’s also a retrospective moment—an exploration of the 2014 Ice Bucket Challenge, which became a viral engine for funding research and, ultimately, accelerated treatment pathways. Dane and Sawyer revisit its impact, both in terms of public visibility and the lasting medical outcomes it helped shape.

For longtime fans of Dane, the episode also dips into career territory. From his breakout on Grey’s Anatomy to the emotional toll of playing Cal Jacobs in Euphoria, Dane reflects on professional highs, personal challenges, and his enduring connection with Ellen Pompeo.

This isn’t a curtain call—it’s a conversation. And it lands at a moment when interest in meaningful, personal storytelling around health, legacy, and resilience continues to grow across streaming platforms.

Eric Dane Speaks: The Diane Sawyer Interview is now streaming on Hulu and Disney+.