Paramount to pay Trump $16m over 60 Minutes Kamala Harris interview
During the month-long settlement talks, some CBS News executives including chief executive Wendy McMahon have left their roles, due to their unwillingness to issue an apology to Trump.
There were also reportedly concerns over whether paying to settle the lawsuit could be viewed as bribing a public official.
A spokesman for Trump's legal team said the settlement was "another win for the American people as he, once again, holds the Fake News media accountable for their wrongdoing and deceit."
He added that CBS and Paramount "realised the strength of this historic case."
CBS has said the broadcast was "not doctored or deceitful".
The Paramount settlement follows a decision by Walt Disney-owned ABC News to settle a defamation case brought by Trump.