Dr. Jumba Jookiba is a major character in the Lilo & Stitch franchise. He is a self-proclaimed evil genius responsible for the creation of the infamous Experiment 626, better known as Stitch, and over 628 other illegal genetic experiments.

Jumba was born on the planet Quelte Quan. There, he created a series of illegal genetic experiments, but was eventually banished as a result. He then bought his own laboratory, where he continued to create more experiments alongside his former college friend Dr. Hämsterviel. The two scientists both graduated from Evil Genius University and managed a business called "Jokes on You". Eventually, both Jumba and Hämsterviel would be arrested, following the creation of Jumba's latest experiment, 626. However, this new experiment proved to help Jumba in more ways than one, having him released from prison and finding him a family that loves him and vice versa.

He is said to be divorced and has mentioned his ex-wife several times (usually in a negative way as she often nags him to get a real job). However, he has stronger respect for his mother.

Jumba is a comical and endearing character, despite his "evil" status. Prior to meeting Lilo, Jumba was somewhat insane and ruthless, engaging in illegal, genetic experimentation for the sole purpose of wreaking havoc across the galaxy. His motivation towards such malice remains unknown, though his previously sadistic nature hints it was merely for his own evil satisfaction and enjoyment. He is more interested in anarchy and chaos, rather than true evilness.

Interestingly, Jumba's switch from villainous to heroic was rather hasty, showing he apparently had some form of moral to him even before meeting Lilo, as he quickly agreed to rescue her after she was wrongfully captured by Captain Gantu, in an attempt to capture Stitch. Upon meeting Lilo, and following his welcome into the Pelekai family, Jumba became rather humble and began to act as a father-like figure towards Lilo, his previously egotistical nature watering down to mere pride and confidence, and his villainy forming into innocent mischief. He is often paired with his friend Pleakley, who was forced to work alongside him to capture Stitch when he was still a menace. The two had a bitter relationship at first, but following the events of the original film, Jumba and Pleakley became the closest of friends.

Ironically, for an evil genius, Jumba is actually very friendly and sociable outside his work. He is also one of the few characters, aside from Lilo, Nani, David, Pleakley, and most of the other experiments, who loves Stitch. In fact, Jumba loves all of his genetic creations, having a sense of paternal pride in them. He speaks with a vague Russian accent, but also uses very poor grammar and refers to himself in the third person.

Though the extent of Jumba's "genius" can be somewhat questionable at times, the scientist proves to be a mastermind in his own right, as well as generally, having the ability to create new, sentient lifeforms single-handedly, as well as a slew of different creations, as seen in the animated series, though they can sometimes cause more havoc than initially intended, even if their purpose was to enhance life's fortunes, rather than cause mayhem.

Jumba is a large, overweight, sloth-like alien, known as a Kweltikwan, with pale pink skin on his face, chest, stomach, and underarms while he has dull purple skin mostly on the back, such as his abdominal and head, with some part forming a "V" outing on the top, and on the over arms and legs. His face and stomach are rotund and rather bulbous, along with his arms and legs are really thick, compared to his floppy ears on the sides of his neck with the innards pink are relatively small. He has a large purple koala-like nose and a wide mouth with large, blunt-edged hippo-like teeth. Jumba has four eyes, two that are large and two that are small on each side, with pale yellow sclerae and black pupils. He has four fingers on each hand yet apparently lack toes. Jumba is mostly bald, only having three short black hairs on the top of his head (after Clip ate his hair).

During his time on Hawaii, and when he's in his "Lilo's uncle" disguise, he wears a yellow Hawaiian shirt, which doesn't fit him well, with a couple of black vertical buttons and red designs on it, blue shorts with white linings, and gray boots with light gray soles. Sometimes his Hawaiian shirt is light blue with white designs.

When he was imprisoned on Prison Asteroid K-37, he wore a prison jumpsuit covered in horizontal dark and light blue stripes.

When he was a scientist, he wore a white lab coat and gray pants.

In his first appearance, Jumba was on trial for creating illegal genetic experiments. While Jumba was imprisoned, Stitch escaped his craft that would have sent him to a desert asteroid for life in exile (in the hopes that he would eventually perish for want of food). The Grand Councilwoman then commanded Jumba to search the island of Hawaii to find and capture Stitch, granting him one of her warriors' plasma cannons in an attempt to stun 626.

Jumba and his new sidekick Pleakley tried numerous plans to capture Stitch, but always failed, mainly due to either their incompetence, Stitch's aggressive nature, Pleakley's insistence on the rule that Jumba should never cause destruction to anyone crossing his path, or all three of them at the same time. When Jumba and Pleakley were camped out on surveillance, Jumba laments that he never gave 626 a greater purpose, wondering what it must be like for 626 to not even have memories to think about in the middle of the night. Once Jumba and Pleakley were fired and scheduled to a prison sentence due to their failure to capture 626 on time, Jumba decided to play by his own rules - which involves causing as much destruction as he wants, much to Pleakley's dismay. A battle between Jumba and Stitch occurred at Lilo's home. Due to the battle, a blaster exploded and Jumba and Pleakley fled from the home.

While Jumba and Pleakley were away, Stitch and Lilo were kidnapped by Captain Gantu. Stitch managed to escape, but was put in shackles by Jumba. Lilo's sister, Nani asked Jumba and Pleakley if they knew where Lilo was located, but the duo had no clue. Stitch convinced Jumba rather easily to help save Lilo. Nani, Stitch, Pleakley, and Jumba set off to rescue Lilo. Once everyone was saved and Gantu was defeated, Jumba helped rebuild Lilo's house and becomes a part of Lilo's ohana along with Pleakley and Stitch.

Jumba reappears in the franchise's second film. In the film, Jumba is kidnapped by Gantu and Dr. Hämsterviel, Jumba's former lab partner who plots to take over the galaxy; originally thought to have been deceased by the events of the film. It is revealed that Jumba created a far greater amount of experiments other than Stitch.

Before his kidnapping, Jumba managed to hide his experiments with Pleakley, though this would only prompt Hämsterviel to hold the scientist for ransom, threatening to kill Jumba unless the experiments were handed over; though Jumba's sass and fearless demeanor prevented the villains from legitimately intimidating him. Pleakley, Nani, and former CIA agent, Cobra Bubbles, constructed a transaction area in defeat. Nevertheless, Lilo and Stitch managed to save both Jumba and the experiments, though they are accidentally set free. In response, Jumba and the others are recruited by the Grand Councilwoman (who was also alerted about the situation regarding Hämsterviel and Jumba) in journeying across the island to find each experiment and turn them from bad to good.

Now residing with Lilo and Stitch in Hawaii, Jumba goes under the guise of Lilo's uncle and plays a major role in the series. With 623 experiments scattered around the island, Jumba provides information for each one that Lilo and Stitch discover and/or capture. In spite of becoming a humble hero, Jumba still strives to keep his evil reputation, but ultimately fails in favor of his family. When an experiment is captured, Lilo and Stitch will take it to Jumba first and foremost. Most of the experiments recognize Jumba and refer to him as their father figure. On many occasions, before an experiment's reformation, the former would go after Jumba to prevent him from revealing the key to their defeat before he can tell Lilo and Stitch.

In the episode, "Ace", it was revealed that Jumba is a member of the Evil Genius Organization (E.G.O.), which is an organization comprised of various evil scientists from across the galaxy. By the end of the episode, as a result of his apparent reformation, Jumba was discharged from the organization.

The episode "The Asteroid" revealed that Jumba suffered from homesickness, and was willing to abandon an endangered Earth if it meant returning to his home planet. However, his attitude shifted upon realizing his desire to stay with Lilo and Stitch.

Also in the series, Jumba and Pleakley even encountered other Disney characters during their adventures such as Penny Proud and Kim Possible. Jumba even mistook Rufus for one of his missing experiments, Experiment 607.

Jumba reappears in this off-shoot sequel. Before either of them ever met Lilo, Jumba was putting the finishing touches on Stitch (known as Experiment 626 then), but before the doctor could release him, 626's molecules had to be charged. While Experiment 626 was charging, intergalactic police officers intruded into the lab and arrested Jumba, leaving 626 incomplete.

Finally, those past events catch up to Stitch and the consequences begin to unfold. During a family night, he notices that Stitch has a glitch which causes him to lose control, and gets worried about him, realizing what was wrong in him. In order to save him, he must build a fusion chamber to recharge him before his molecules are out of power, or else he will die.

Due to the lack of technology, Jumba and Pleakley are forced to use domestic appliances, and when it was finally "finished", it exploded and Jumba, losing hope, revealed to Pleakley that it was just an order from a catalog. He believes he cannot actually make the machine on his own, but is given the will to try after encouragement from Pleakley. When he finally manages to built it properly, he discovers that Stitch is gone, and goes out with the others to find him.

In the end, after the fusion chamber failed to recharge Stitch, Jumba is clearly devastated about his "death", tightly holding him in his arms, but Lilo miraculously managed to resuscitate Stitch when she took him into her arms, crying because of her deep love for Stitch as part of her family; Jumba gained Lilo's gratitude and love by showing a deep, loving concern for Stitch. It appears that his attempt to recharge Stitch had succeeded after all.

When Stitch is playing soccer, his ball lands inside Jumba's ship, where he discovers the ship's laboratory, and the ship's computer scans and identifies Stitch as Experiment 626. After showing a list of experiments and their components used to create Stitch, Jumba enters the ship's lab and offers Stitch a choice between milk and cookies. After Jumba detects that Stitch is curious about his origins, Jumba reveals that he pursued some of the most horrible and fearsome beasts to create the ultimate monster unlike any he had ever created before. Jumba then goes on to say that the creation of Stitch didn't turn out exactly as he had planned, because Stitch discovered a family in Lilo, Nani, David, Jumba, and Pleakley when he landed in Kauai. Jumba then says that of all the experiments he had ever created, Stitch is his greatest success and that he is very proud of him.

Three years after Jumba's experiments were scattered across Kauai, Hawaii, Lilo and Stitch had rounded up and reformed 624 experiments. Jumba was given the opportunity to return to his old laboratory by the Grand Councilwoman. At first, he did not want to hurt Lilo's feelings by leaving, but she agreed to let him go, giving him an Elvis record to remember her by. However, Hämsterviel escaped from prison with the help of the former Captain Gantu, who had been retired from his position forcibly by the Grand Councilwoman three years prior to these events and held Jumba hostage in his own lab, forcing him to create a new experiment, which ends up being named Leroy. However, Jumba used the record Lilo gave him to program a shut-off switch for Leroy: if he hears the song "Aloha ʻOe", he will glitch and switch off (but will not die like Stitch would have as shown at the end of Stitch Has a Glitch). When asked what he would like as a reward, he decides to give up his laboratory and return to Earth to become part of Lilo's family once again.

In the anime series, Jumba was given a mission by the Grand Councilwoman to watch over Stitch as he recently began a destructive rampage after Lilo grew up, went off to college, and found a boyfriend. Jumba eventually lost Stitch, but quickly reunited with him in a small island known as Izayoi. When he arrived, he met Stitch's newest friend Yuna and learns about Stitch's latest goal to do good deeds and obtain ultimate power. Jumba agrees to assist Stitch and stays on the island.

Sometime after being taken into custody by Federation forces shortly before the first film, the computers at Jumba's labs were hacked by space pirates hoping to re-create Experiment 626. When these attempts failed, they decided to kidnap Stitch. While in pursuit of the pirates, but unaware of Stitch's escape, Jumba and Pleakley are taken before the Grand Councilwoman who explains the situation and again assigns them to take Stitch back into protective custody and keep him out of space pirates' hands. After seeing that Stitch has found a new family in China, Jumba decides to stay and assist in combating the pirates.

Jumba plays a prominent role in Experiment 626, where the goal is to help Jumba create new experiments and fuel teleporting machines that allow 626 to move between worlds.

While serving time for illegal genetic experimentation in a cell within the Turo Prison Block, Jumba witnesses Terra fight off several Unversed. He persuades the Keyblade wielder to release him so that the two may rescue a "constructive" creature of his own creation called "Experiment 626." Terra agrees and the two set off to find 626 together. When they finally find the small extraterrestrial encased in a pod within the Confinement Room, Jumba sets him free and reveals that he is meant to be an evil and malevolent creature whose only instinct is to destroy everything he touches. 626 then rushes at Terra and steals his Wayfinder, the Keyblade wielder ordering him to return it because his "friend" gave it to him. Jumba later laughs off the idea that 626 could understand the concept of friendship, but he is greatly surprised when his creation drops the Wayfinder and scuttles off. Jumba finds Terra's theory that 626 isn't evil at all and merely craves friends impossible, and he gives him another demonstration of his "evil geniusness" by activating Experiment 221 for the Keyblade wielder to battle. Terra is victorious and he and Jumba notice 626's return to the Confinement Room after 221 returns to pod form. Jumba watches Terra try to explain friendship to 626, but he angrily interferes with Terra's discussion, as things such as friendship would corrupt his creation's original purpose. He tells 626 that he needs to be fixed, but alarms begin to sound and an announcement is made that 626 and two prisoners have escaped. Terra flees Deep Space, leaving Jumba and 626 behind.

Aqua is the next to visit Deep Space, where she is taken by Captain Gantu before the Grand Councilwoman after destroying several Unversed. The Grand Councilwoman tells Aqua that the Unversed are getting in the way of the apprehension of Jumba and Experiment 626, and she asks the Keyblade wielder to destroy them and also make an attempt to capture Jumba and his experiment intact. Aqua agrees to do the task as asked and departs, much to Gantu's displeasure now that his duties have been assigned to a stranger. The Keyblade Master eventually finds the fugitives on the Launch Deck, where Jumba is attempting to recapture 626 so that he may fix him. Aqua stops Jumba and 626 and announces that she has been authorized to arrest them. When 626 charges at her to reclaim the Wayfinder he had previously made and left behind in the Turo Prison Block, Jumba explains to Aqua that the reason his creation is familiar with the shape of the Wayfinder and its purpose is of his previous encounter with Terra. Jumba then goes on to complain to Aqua about the negative impact Terra has had on 626, but Gantu soon appears and attempts to put an end to both Jumba and his supposedly evil creation. Aqua teams up with 626 to battle Gantu and, upon their victory, the Grand Councilwoman arrives to apprehend the two fugitives.

Jumba appears in the mobile fighting game. To unlock him, you need 10 tokens.

His interactions are the same as in the franchise, and in his victory pose he laughs in a terrifying way despite being reformed.

His mission friends are Stitch, Pleakley and Animal from The Muppets.

In World of Color: Season of Light, Jumba appears in the segment centered around Lilo & Stitch where he, dressed as Santa Claus, joins his extended family in celebrating the holidays.

Jumba makes occasional appearances at Tokyo Disneyland and Tokyo DisneySea, often in various shows and parades. Like many of the walk-around versions of the supporting characters of the Lilo & Stitch franchise though, he hasn't really been used elsewhere, as the film and television series are some of the most popular Disney media in Japan.

Jumba made appearances at Stitch's Hawaiian Paradise Party in Disney Village.

Jumba states in "The Asteroid" that he finds chewing food rather annoying because on his home planet, nutrients are absorbed through the skin. However, at the end of the same episode, he admits that he enjoys pizza, and in "Holio", he mentions that he likes eating pastrami.

We learn in "The Asteroid" that Jumba had been banished from his home planet for evil genius research, but in "Sinker", he mentions about having given presents to his evil genius family back home (hinting that he may come from a family of evil geniuses), implying while he cannot go back to his home planet, he is allowed to send gifts there.

Jumba was David Ogden Stiers' last character in the Disney Animated Canon, 16 years before his death in 2018.