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EMCrit 402 - Sea Change on Salt Water (More Rapid Sodium Normalization in Hyponatremia)? with KidneyBoy

Published 20 hours ago2 minute read

You are here: Home / EMCrit / EMCrit 402 – Sea Change on Salt Water (More Rapid Sodium Normalization in Hyponatremia)? with KidneyBoy

So there is a contentious debate in the nephrology world regarding the safe rates of correction of hyponatremia. For at least a decade, in chronic hyponatremia, has been the watch word. Now in addition to questions as to whether that actually prevents osmotic deymelination, there have been a number of papers published showing an association with slower correction rates and increased mortality. None of this evidence is from high-quality RCTs unfortunately. To shed light on this issue, I brought on the KidneyBoy, Joel Topf, MD.

Joel Topf is a nephrologist in Detroit working for St Clair Specialty Physicians. He is faculty for the Nephrology Fellowship at St John Providence.

Ayus et al. Systematic Review on Hyponatremia Correction Rates

Note: vet these recs with your own nephrology service before using!!

A counter-point from Stern et al.

European Guidelines

NephJC Comparison of Us and Europe Hyponatremia
from Neph Journal Club

NEJM

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Scott Weingart, MD FCCM

Editor-in-Chief, at EMCrit.org

An ED Intensivist from NY.
Professor
Nassau University Medical Center
No conflicts of interest (coi).

Scott Weingart, MD FCCM

Scott Weingart, MD FCCM. EMCrit 402 – Sea Change on Salt Water (More Rapid Sodium Normalization in Hyponatremia)? with KidneyBoy. EMCrit Blog. Published on June 20, 2025. Accessed on June 21st 2025. Available at [https://emcrit.org/emcrit/more-rapid-sodium-normalization-hyponatremia/ ].

The course director, Dr. Scott D. Weingart MD FCCM, reports no relevant financial relationships with ineligible companies. This episode’s speaker(s) report no relevant financial relationships with ineligible companies unless listed above.

Original Release: June 20, 2025
Date of Most Recent Review: June 20, 2025
Termination Date: Jul 1, 2027

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