Wayne Rooney, United's all-time record goal-scorer, last managed at Soccer Aid in 2020 and played in the game the following year.
He said: "It's great to lace up the old boots again - and see some old friends - but the cause is the real reason we are doing this."
He'll be playing alongside former teammates like Gary Neville and Paul Scholes, plus Lionesses Jill Scott, Steph Houghton and Toni Duggan.
There will also be famous names from outside of football, such as Olympic gold medallist Sir Mo Farah, singer Tom Grennan and former One Direction member Louis Tomlinson.
Louis said: "It's about ten years since I last turned out for Soccer Aid, so I thought it was about time I returned to the pitch.
"As everyone knows, I am a massive football fan so playing with some legends of the game is a dream come true."
Gladiator Diamond will be back in action.
The charity match will see an England team of former pros and celebrities take on a Soccer Aid world eleven.
More famous faces are set to be revealed in the coming weeks but those announced for the world team in include former football stars Leonardo Bonucci and Nadia Nadim as well as Gladiator Diamond, real name Livi Sheldon, who will be making her second Soccer Aid appearance in a row.
The charity match between England and the Soccer Aid world eleven will take place on Sunday 15 June.
